CDC warns of serious monkey disease as Ohio reports death of monkey patient


The U.S. Centers for Disease Control and Prevention issued a new warning to health care providers Thursday about serious illness in people with the monkey.

The alert comes as Ohio reports the death of a person with rabies, the third known death of a patient with rabies in the United States.

Ohio listed the death in an update to its online monkeypox outbreak dashboard. No further details were released, including whether the death was caused by the virus itself or whether other conditions contributed.

“CDC is aware of the death of an individual in Ohio who had serious illness and tested positive for monkeypox,” Kathleen Conley, a spokeswoman for the US Centers for Disease Control and Prevention, told CNN on Thursday. CNN has reached out to the Ohio Department of Health for more information.

The first U.S. death from monkeypox was confirmed this month in Los Angeles County. The county’s public health department and the CDC said the person had a severely weakened immune system and was hospitalized. According to the department, no further information will be made public.

A person with a monkey in Harris County, Texas, died in August, but the role of the virus in the death has not been confirmed.

Deaths from monkeypox are extremely rare, and infants, pregnant women, and those with weakened immune systems are at greater risk. Among the more than 67,000 cases reported worldwide in the current outbreak, there have been 27 deaths, according to the World Health Organization.

More than 25,000 cases of monkeypox have been reported in the United States, but recent case trends suggest the outbreak is slowing in the United States.

The decline in the number of cases could be a reflection of the number of people who are vaccinated against the virus. This week, the CDC announced that it is expanding eligibility for the Jynneos monkeypox vaccine to people at higher risk who have not been exposed to the virus.

According to data released by the CDC on Wednesday, men at high risk of getting HIV because they have sex or are living with HIV were 14 times more likely than those who were at least two weeks without the vaccine. after the first dose of the vaccine.

The CDC said Thursday that some people infected with the monkey during the U.S. outbreak had “severe manifestations” of the disease, including prolonged hospitalizations or “significant” health problems.

The agency’s health alert says severe monkeypox can happen to anyone, and most people diagnosed in this outbreak have had mild to moderate illness. Most people with severe disease have had HIV with “severe immunosuppression.”

Some of the serious diseases were:

  • Coalescent or necrotic lesions requiring extensive surgical care or amputation of an extremity
  • Injuries to sensitive areas such as the mouth, urethra, rectum or vagina that cause severe pain and affect daily activities
  • Intestinal lesions with significant inflammation leading to obstruction
  • Lesions that cause scarring have “significant” effects on areas such as the intestines or face.
  • Multiple organ system involvement and associated conditions such as encephalitis, myocarditis, conjunctivitis and corneal ulcers

The advisory urges health care providers to be aware of risk factors for severe monkeypox, and says that anyone with suspected or confirmed monkeypox should be tested for HIV. Providers should also check to see if another condition or medication may weaken the person’s immune system.

Monkey treatment for people with weakened immune systems should include stopping drugs that can affect the immune system, giving people with HIV antiretroviral therapy, and possibly using medications like tecovirimat, also known as Tpoxx.

The CDC says people who were sexually exposed to monkeypox should be tested for HIV and other sexually transmitted diseases.